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Which of these statements is NOT true about complement?


A) Complement is a complex of plasma proteins that are activated in the presence of pathogens.
B) Complement is required for formation of antigen-antibody complexes.
C) Complement forms holes in bacterial membranes and allows fluid and salts to enter a bacterial cell.
D) Complement attracts phagocytes to the bacterial cell and increases its likelihood of being engulfed.

E) None of the above
F) All of the above

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Which of the following definitions best describes the role of pathogen-associated molecular patterns (PAMP's) ?


A) PAMP's are molecules on a pathogen that can be recognized by the host organisms immune system.
B) PAMP's are molecules on a host cell that can be recognized by the pathogen's attack system.
C) PAMP's are molecules on the host immune system that cause it to attack itself as in autoimmune disorders.
D) PAMP's are molecules on a pathogen that can be recognized by other pathogens so they can exchange genetic material with each other.

E) B) and D)
F) A) and B)

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The first line of defense against invading microorganisms is nonspecific.

A) True
B) False

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True

Which kind of T cells regulate the immune response by producing stimulatory lymphokines?


A) memory T cells (TM)
B) suppressor T cells (TS)
C) cytotoxic T cells (TC)
D) helper T cells (TH)

E) A) and C)
F) A) and D)

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Cytokines


A) are soluble proteins that act as signaling molecules to stimulate white blood cells.
B) are secreted by macrophages to stimulate the replication of cancer cells.
C) repel neutrophils from the site of infection.
D) inhibit production of T and B cells.

E) C) and D)
F) A) and B)

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Which of the following immunodeficiency disorders could possibly be treated or prevented by gene therapy during the embryological stage?


A) X-linked agammaglobulinemia (XLA)
B) AIDS
C) Asthma
D) None of these disorders can be treated by gene therapy during the embryological stage.

E) B) and C)
F) A) and D)

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Which type of immunity is characterized by the production of receptors that will bind to specific antigens?


A) adaptive
B) innate
C) both adaptive and innate
D) neither adaptive or innate

E) All of the above
F) B) and C)

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Which of the following characterize B cells?


A) They function in antibody mediated immunity against bacteria.
B) They directly recognize antigens and undergo clonal selection.
C) They are manufactured and mature in the bone marrow.
D) All of the choices characterize B cells.
E) None of the choices characterize B cells.

F) C) and E)
G) B) and D)

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D

What are the potential symptoms of a person who is suffering from anaphylactic shock?


A) The smooth muscle of the bronchi may constrict.
B) An increased dilation of the capillaries that can lower the blood pressure.
C) The release of a massive amount of histamine within the blood stream.
D) All of the answer choices are potential symptoms of a person who is suffering from anaphylactic shock.

E) A) and D)
F) A) and C)

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Maturation of T cells occurs in the


A) bone marrow.
B) lymph nodes.
C) spleen.
D) thymus.
E) Peyer's patches.

F) A) and B)
G) None of the above

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Which of the following statements about B cells is true?


A) B cells develop and mature in the bone marrow.
B) B cells carry receptor molecules on their cell surfaces.
C) B cells change into plasma cells after encountering an antigen and then produce antibodies.
D) Some B cells become memory cells.
E) All of these are true.

F) B) and E)
G) A) and E)

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Which statement is NOT true of the T cells?


A) T cells mature in the thymus.
B) T cells carry receptor molecules on their cell surfaces.
C) T cells change into plasma cells and produce antibodies when stimulated.
D) T cells require presentation of antigens by macrophages before they are able to recognize the antigen.

E) A) and C)
F) B) and D)

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C

Compare the primary and secondary antibody titre responses during immunization by drawing a graph of "Plasma Antibody Concentration" vs."Time." Indicate on the graph the time of first and second exposure.The y-axis may be quantified as low to high and need not report specific number quantities.

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A primary response occurs after the firs...

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Interferon is a protein that binds to the receptors of non-infected cells causing them to produce substances that interfere with viral replication.

A) True
B) False

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Anaphylactic shock


A) is characterized by a sudden and life-threatening drop in blood pressure.
B) occurs when the allergen has entered the bloodstream.
C) is an immediate allergic reaction.
D) All of these are true.
E) None of these are true.

F) C) and D)
G) B) and D)

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Immediate allergic responses are caused by ________ antibodies.


A) IgA
B) IgG
C) IgE
D) IgM
E) IgD

F) All of the above
G) B) and C)

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Nonspecific defenses against disease include all of the following EXCEPT


A) skin and mucous membranes.
B) natural killer cells.
C) inflammatory reaction.
D) antibodies.
E) complement.

F) A) and C)
G) C) and D)

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The reason that cellular slime molds are being used to study the evolution of the immune system is because


A) cells within the multicellular slug will perform specialized function similar to that of neutrophils and macrophages.
B) cells within the single-celled slug will perform specialized function similar to that of neutrophils and macrophages.
C) cells within the multicellular slug will perform specialized function similar to that of red blood cells.
D) the slug is capable of preventing pathogens from being able to infect it.
E) None of these reasons are why cellular slime molds are being used for studying the evolution of the immune system.

F) B) and D)
G) A) and E)

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Which of the following organisms is helping scientists better understand the evolution of the immune system because they have a unique feature during their lifecycle?


A) cellular slime molds
B) B cells
C) archaea
D) planaria
E) viruses

F) C) and E)
G) A) and D)

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What specific part of the antibody determines the class of the antibody?


A) variable region of the light chain and heavy chain
B) antigen binding sites
C) constant region
D) All of these are correct.
E) None of these are correct.

F) A) and B)
G) B) and C)

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