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Exam 18: Breast

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Question 1

Multiple Choice

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A 55 year old man was undergoing oestrogen treatment for his prostatic adenocarcinoma.He noticed bilateral swelling in his breasts.Because of the cosmetic nature of the disorder,the bilateral breast tissue was removed,and a representative section is shown in the accompanying photomicrograph.Which one of the following is the best diagnosis?

A) Ductal carcinoma in situ
B) Fibroadenoma
C) Fibrocystic change
D) Gynaecomastia
E) Infiltrating ductal carcinoma
F) Infiltrating lobular carcinoma
G) Lobular carcinoma in situ

H) C) and E)
I) A) and B)

Correct Answer

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D

Question 2

Multiple Choice

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A 28 year old woman consulted her GP because she felt a mass in her breast,just below the nipple.She had also noted a bloody discharge from the same nipple,and was quite concerned.The GP told her it was likely benign,and the mass was later removed surgically.A representative section is shown in the accompanying photomicrograph.Which one of the following is the best diagnosis?

A) Ductal carcinoma in situ
B) Fibroadenoma
C) Fibrocystic change
D) Gynaecomastia
E) Infiltrating ductal carcinoma E.Infiltrating ductal carcinoma
F) Infiltrating lobular carcinoma
G) Intraductal papilloma
H) Lobular carcinoma in situ

I) F) and G)
J) F) and H)

Correct Answer

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G

Question 3

Multiple Choice

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A 49 year old woman found a mass in each of her breasts.After consultation with a surgeon,bilateral biopsies were done,revealing the histology seen in the accompanying photomicrograph.How would you classify the malignant cells (M) seen?

A 23 year old woman noted a firm,mobile,2 cm mass in her right breast.Alarmed,she consulted her GP,and it was removed.A representative section of the mass is shown in the accompanying photomicrograph.Which one of the following is the best diagnosis?

A 58 year old woman noted a mass in her breast,for which she sought advice from her GP.The physician felt the mass,but also noticed skin retraction over the lesion.A biopsy was done,revealing the histological appearance shown in the accompanying low power photomicrograph.Which one of the following is the best diagnosis?

A 40 year old woman consulted her GP because she felt a lump in her breast.The GP found the lump and felt that,since the mass seemed to change in size with her menstrual periods,it was likely a benign process.Because she had a sister with breast cancer,and to avoid excessive worry on the part of the patient,a biopsy was performed.A representative section is shown in the accompanying photomicrograph.Which one of the following is the best diagnosis?

A 63 year old woman consulted her GP because of a rash on her left nipple.It had been weeping clear fluid for some weeks,and was reddened.A biopsy was done,and a representative section is shown in the accompanying photomicrograph.Which one of the following conclusions is warranted?